BDBM50222823 2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isonicotinic acid::CHEMBL430393

SMILES OC(=O)c1ccnc(NC(=O)COc2ccc(cc2)C23CC4CC(CC(C4)C2)C3)c1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222823   

TargetHypoxia-inducible factor 1-alpha(Human)
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222823(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50: 800nMAssay Description:Inhibition of hypoxia induced HIF1-alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222823(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1-alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222823(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1-alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed