BDBM50222732 (5S,11S,13aR)-5-benzyl-8,8-dimethyl-11-[5-(pyridin-2-yldisulfanyl)-pentyl]-decahydro-3a,6,9,12-tetraaza-cyclopentacyclododecene-4,7,10,13-tetraone::CHEMBL238829::cyclo(-L-Am7(S2Py)-Aib-L-Phe-D-Pro-)

SMILES CC1(C)NC(=O)[C@H](CCCCCSSc2ccccn2)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O

InChI Key InChIKey=GNIYZHFLRFNYMZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50222732   

TargetHistone deacetylase 6(Mouse)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732(cyclo(-L-Am7(S2Py)-Aib-L-Phe-D-Pro-) | (5S,11S,13a...)
Affinity DataIC50: 40nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732(cyclo(-L-Am7(S2Py)-Aib-L-Phe-D-Pro-) | (5S,11S,13a...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732(cyclo(-L-Am7(S2Py)-Aib-L-Phe-D-Pro-) | (5S,11S,13a...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732(cyclo(-L-Am7(S2Py)-Aib-L-Phe-D-Pro-) | (5S,11S,13a...)
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732(cyclo(-L-Am7(S2Py)-Aib-L-Phe-D-Pro-) | (5S,11S,13a...)
Affinity DataIC50: 404nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732(cyclo(-L-Am7(S2Py)-Aib-L-Phe-D-Pro-) | (5S,11S,13a...)
Affinity DataIC50: 39nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed