BDBM50222625 CHEMBL142050

SMILES CC(C)N1CCC(CC1)Nc1cc2N(C(=O)NCc2c(c1)-c1ccccc1Cl)c1c(Cl)cccc1Cl

InChI Key InChIKey=XEQBKWGVMSNLAI-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50222625   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck

Curated by ChEMBL

LigandBDBM50222625(CHEMBL142050)Copy SMILESCopy InChI

Affinity DataIC50: 1.60nMAssay Description:Inhibition of p38 MAP kinaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/19/2018
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck

Curated by ChEMBL

LigandBDBM50222625(CHEMBL142050)Copy SMILESCopy InChI

Affinity DataIC50: 31nMAssay Description:Inhibition of p38 kinase related TNF-alpha releaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/19/2018
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL