BDBM50222621 CHEMBL142463

SMILES CC(C)N1CCC(CC1)Nc1cc2n(-c3c(Cl)cccc3Cl)c(=O)ccc2c(n1)-c1ccccc1Cl

InChI Key InChIKey=JEBBTQWFFYQVCM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50222621   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck

Curated by ChEMBL

LigandBDBM50222621(CHEMBL142463)Copy SMILESCopy InChI

Affinity DataIC50: 1.10nMAssay Description:Inhibition of p38 MAP kinaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/19/2018
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck

Curated by ChEMBL

LigandBDBM50222621(CHEMBL142463)Copy SMILESCopy InChI

Affinity DataIC50: 51nMAssay Description:Inhibition of p38 kinase related TNF-alpha releaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/19/2018
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL