BDBM50222489 (R)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-5-yloxy)propyl)-2-hydroxy-N-methylacetamide::CHEMBL250132

SMILES C[C@H](CN(C)C(=O)CO)Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12

InChI Key InChIKey=ZROBAJVGRYCCGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50222489   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222489((R)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222489((R)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed