BDBM50222434 (R)-4-(6,7-dimethoxyquinazolin-4-yl)-2-methyl-1-phenylbut-3-yn-2-ol::CHEMBL250525

SMILES COc1cc2ncnc(C#CC(C)(O)Cc3ccccc3)c2cc1OC

InChI Key InChIKey=DCFLKULIIIPJPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222434   

TargetEpidermal growth factor receptor(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50222434((R)-4-(6,7-dimethoxyquinazolin-4-yl)-2-methyl-1-ph...)
Affinity DataIC50: 9nMAssay Description:Inhibition of partially purified EGFR tyrosine kinase from human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed