BDBM50222428 (R)-4-(6,7-dimethoxyquinazolin-4-yl)-N,N-diethyl-2-methyl-1-phenylbut-3-yn-2-amine::CHEMBL429300

SMILES CCN(CC)C(C)(Cc1ccccc1)C#Cc1ncnc2cc(OC)c(OC)cc12

InChI Key InChIKey=BBMKJPDKBXILOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222428   

TargetEpidermal growth factor receptor(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50222428((R)-4-(6,7-dimethoxyquinazolin-4-yl)-N,N-diethyl-2...)
Affinity DataIC50: 3nMAssay Description:Inhibition of partially purified EGFR tyrosine kinase from human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed