BDBM50222422 6,7-diethoxy-4-(2-(3-(4-fluorophenyl)-1H-pyrazol-4-yl)ethynyl)quinazoline::CHEMBL251125

SMILES CCOc1cc2ncnc(C#Cc3c[nH]nc3-c3ccc(F)cc3)c2cc1OCC

InChI Key InChIKey=AHECKEJZVOJBKG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222422   

TargetEpidermal growth factor receptor(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50222422(6,7-diethoxy-4-(2-(3-(4-fluorophenyl)-1H-pyrazol-4...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of partially purified EGFR tyrosine kinase from human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed