BDBM50222421 CHEMBL250524::N-(4-(6,7-dimethoxyquinazolin-4-yl)-2-methylbut-3-yn-2-yl)-N-methylbenzenamine

SMILES COc1cc2ncnc(C#CC(C)(C)N(C)c3ccccc3)c2cc1OC

InChI Key InChIKey=BQXIAZSINPRHQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222421   

TargetEpidermal growth factor receptor(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50222421(N-(4-(6,7-dimethoxyquinazolin-4-yl)-2-methylbut-3-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of partially purified EGFR tyrosine kinase from human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed