BDBM50222417 4-(3,3-dimethyl-4-phenylbut-1-ynyl)-6,7-dimethoxyquinazoline::CHEMBL399953

SMILES COc1cc2ncnc(C#CC(C)(C)Cc3ccccc3)c2cc1OC

InChI Key InChIKey=RVEDAUKOXMSMKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222417   

TargetEpidermal growth factor receptor(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50222417(4-(3,3-dimethyl-4-phenylbut-1-ynyl)-6,7-dimethoxyq...)
Affinity DataIC50: 13nMAssay Description:Inhibition of partially purified EGFR tyrosine kinase from human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed