BDBM50222357 3-(((R)-1-((S)-1-(4-aminophenyl)ethyl)-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl)(propyl)amino)-3-oxopropanoic acid::CHEMBL392690

SMILES CCCN(C(=O)CC(O)=O)C1=C(C)C[C@@H](N([C@@H](C)c2ccc(N)cc2)C1=O)c1ccccc1

InChI Key InChIKey=CCFUBKFBAQEAGV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50222357   

TargetIntegrin alpha-V/beta-3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50222357(3-(((R)-1-((S)-1-(4-aminophenyl)ethyl)-4-methyl-2-...)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of integrin alpha-V-beta-3-mediated SK-MEL-24 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50222357(3-(((R)-1-((S)-1-(4-aminophenyl)ethyl)-4-methyl-2-...)
Affinity DataIC50: 3.51E+4nMAssay Description:Inhibition of integrin alpha-5-beta-1-mediated K562 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50222357(3-(((R)-1-((S)-1-(4-aminophenyl)ethyl)-4-methyl-2-...)
Affinity DataIC50: 71nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50222357(3-(((R)-1-((S)-1-(4-aminophenyl)ethyl)-4-methyl-2-...)
Affinity DataIC50: 57nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed