BDBM50222293 4'-chloro-7,8-dihydroxyisoflavone::CHEMBL241814

SMILES Oc1ccc2c(occ(-c3ccc(Cl)cc3)c2=O)c1O

InChI Key InChIKey=OXYPFUPOFGTDMR-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50222293   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222293(4'-chloro-7,8-dihydroxyisoflavone | CHEMBL241814)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 15-hLO2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222293(4'-chloro-7,8-dihydroxyisoflavone | CHEMBL241814)
Affinity DataIC50: 480nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222293(4'-chloro-7,8-dihydroxyisoflavone | CHEMBL241814)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50222293(4'-chloro-7,8-dihydroxyisoflavone | CHEMBL241814)
Affinity DataEC50:  4.02E+4nMAssay Description:Inhibition of PI3Kalpha H1047R mutant (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50222293(4'-chloro-7,8-dihydroxyisoflavone | CHEMBL241814)
Affinity DataEC50:  1.78E+4nMAssay Description:Inhibition of wild type PI3Kalpha (unknown origin) after 40 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed