BDBM50222223 CHEMBL400229::methyl 2-(3-(biphenyl-4-yl)-2-((5-(dimethylamino)pentyl)(methyl)amino)-3,4-dihydroquinazolin-4-yl)acetate::{3-biphenyl-4-yl-2-[(5-dimethylamino-pentyl)-methyl-amino]-3,4-dihydro-quinazolin-4-yl}-acetic acid methyl ester

SMILES COC(=O)CC1N(C(=Nc2ccccc12)N(C)CCCCCN(C)C)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=WSNHBKIWKNYYGN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222223   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50222223({3-biphenyl-4-yl-2-[(5-dimethylamino-pentyl)-methy...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human T-type calcium channel alpha1G in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50222223({3-biphenyl-4-yl-2-[(5-dimethylamino-pentyl)-methy...)
Affinity DataIC50: 230nMAssay Description:Inhibition of T-type calcium channel Cav3.1 alpha-1G subunit expressed in HEK293 cells assessed as calcium current by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50222223({3-biphenyl-4-yl-2-[(5-dimethylamino-pentyl)-methy...)
Affinity DataIC50: 230nMAssay Description:Inhibition of T-type calcium channel Cav3.1 alpha1G expressed in HEK293 cells by whole cell patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed