BDBM50222167 2-amino-N-{(S)-1-[1-(2-benzylcarbamoyl-ethyl)-1H-tetrazol-5-yl]-2-benzyloxy-ethyl}-2-methyl-propionamide::CHEMBL393321

SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCC(=O)NCc1ccccc1

InChI Key InChIKey=XCNYRQGZBZENQU-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50222167   

TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222167(2-amino-N-{(S)-1-[1-(2-benzylcarbamoyl-ethyl)-1H-t...)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human GHS receptor expressed in H4 glioma cells assessed as intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222167(2-amino-N-{(S)-1-[1-(2-benzylcarbamoyl-ethyl)-1H-t...)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [125I]ghrelin from human GHSR1a after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed