BDBM50222159 (S)-N-(1-(1-(3-(methylsulfonamido)benzyl)-1H-tetrazol-5-yl)-2-(benzyloxy)ethyl)-2-amino-2-methylpropanamide::CHEMBL392522

SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1Cc1cccc(NS(C)(=O)=O)c1

InChI Key InChIKey=CCQIXGIFWSMQEC-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50222159   

TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222159((S)-N-(1-(1-(3-(methylsulfonamido)benzyl)-1H-tetra...)
Affinity DataEC50:  116nMAssay Description:Agonist activity at human GHS receptor expressed in H4 glioma cells assessed as intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222159((S)-N-(1-(1-(3-(methylsulfonamido)benzyl)-1H-tetra...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]ghrelin from human GHSR1a after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed