BDBM50222148 (S)-2-amino-N-(2-(benzyloxy)-1-(1-(2-cyanoethyl)-1H-tetrazol-5-yl)ethyl)-2-methylpropanamide::CHEMBL236038

SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCC#N

InChI Key InChIKey=MYJPZNZBOVFLEU-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50222148   

TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222148((S)-2-amino-N-(2-(benzyloxy)-1-(1-(2-cyanoethyl)-1...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GHS receptor expressed in H4 glioma cells assessed as intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222148((S)-2-amino-N-(2-(benzyloxy)-1-(1-(2-cyanoethyl)-1...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GHS receptor expressed in H4 glioma cells assessed as intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222148((S)-2-amino-N-(2-(benzyloxy)-1-(1-(2-cyanoethyl)-1...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at GHS receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222148((S)-2-amino-N-(2-(benzyloxy)-1-(1-(2-cyanoethyl)-1...)
Affinity DataKi:  2.94E+3nMAssay Description:Displacement of [125I]ghrelin from human GHSR1a after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222148((S)-2-amino-N-(2-(benzyloxy)-1-(1-(2-cyanoethyl)-1...)
Affinity DataKi:  2.94E+3nMAssay Description:Agonist activity at human GHS receptor expressed in H4 glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed