BDBM50222100 CHEMBL329005

SMILES Fc1ccc(Sc2nc3CNC(=O)N(c3cc2N2CCCCC2)c2c(Cl)cccc2Cl)c(F)c1

InChI Key InChIKey=QFMUQVZWWIIJOR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50222100   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222100(CHEMBL329005)
Affinity DataIC50: 500nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222100(CHEMBL329005)
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed