BDBM50222007 (4R,6S,E)-6-(2-(7-chloro-6-fluoro-4-(3-methoxyphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL239448

SMILES COc1cccc(Sc2c(\C=C\[C@@H]3C[C@@H](O)CC(=O)O3)cnc3cc(Cl)c(F)cc23)c1

InChI Key InChIKey=XFJAPYVRNNFBBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222007   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50222007((4R,6S,E)-6-(2-(7-chloro-6-fluoro-4-(3-methoxyphen...)
Affinity DataIC50: 9.24E+3nMAssay Description:Inhibition of Holtzman-Sprague-Dawley rat liver HMG CoA reductase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed