BDBM50222000 (4R,6S,E)-6-(2-(6-fluoro-4,7-bis(phenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL239665

SMILES O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1cnc2cc(Sc3ccccc3)c(F)cc2c1Sc1ccccc1

InChI Key InChIKey=VCHAKTOMDKELJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222000   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50222000((4R,6S,E)-6-(2-(6-fluoro-4,7-bis(phenylthio)quinol...)
Affinity DataIC50: 4.41E+3nMAssay Description:Inhibition of Holtzman-Sprague-Dawley rat liver HMG CoA reductase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed