BDBM50221996 (4R,6S,E)-4-hydroxy-6-(2-(4-(4-isopropylphenylthio)quinolin-3-yl)vinyl)-tetrahydropyran-2-one::CHEMBL239242

SMILES CC(C)c1ccc(Sc2c(\C=C\[C@@H]3C[C@@H](O)CC(=O)O3)cnc3ccccc23)cc1

InChI Key InChIKey=BXEXFNXNQJTATD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221996   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50221996((4R,6S,E)-4-hydroxy-6-(2-(4-(4-isopropylphenylthio...)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of Holtzman-Sprague-Dawley rat liver HMG CoA reductase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed