BDBM50221994 (4R,6S,E)-6-(2-(7-chloro-6-fluoro-4-(4-isopropylphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL239449

SMILES CC(C)c1ccc(Sc2c(\C=C\[C@@H]3C[C@@H](O)CC(=O)O3)cnc3cc(Cl)c(F)cc23)cc1

InChI Key InChIKey=PYIOSNBMOACZFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221994   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50221994((4R,6S,E)-6-(2-(7-chloro-6-fluoro-4-(4-isopropylph...)
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibition of Holtzman-Sprague-Dawley rat liver HMG CoA reductase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed