BDBM50221662 CHEMBL320658

SMILES [#6]-[#8]-c1c(-[#8])cc(-[#8])c(-[#6](=O)-c2c(-[#8])cc(-[#8])cc2-[#8])c1-[#6]\[#6]=[#6](/[#6])-[#6]

InChI Key InChIKey=IOUVLFDNMGPOMB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50221662   

TargetSphingomyelin phosphodiesterase [1-45,48-631](Human)
Keio University

Curated by ChEMBL
LigandPNGBDBM50221662(CHEMBL320658)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibitory activity against Acid sphingomyelinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
Keio University

Curated by ChEMBL
LigandPNGBDBM50221662(CHEMBL320658)
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50221662(CHEMBL320658)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed