BDBM50221660 CHEMBL109045

SMILES [#6]-[#8]-c1cc(-[#6](=O)-c2c(-[#8])cc(-[#8])c(-[#6]\[#6]=[#6](/[#6])-[#6])c2-[#8])c(-[#8])cc1-[#8]

InChI Key InChIKey=ZXWVRKRYHJUPAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50221660   

TargetSphingomyelin phosphodiesterase 2(Human)
Keio University

Curated by ChEMBL
LigandPNGBDBM50221660(CHEMBL109045)
Affinity DataIC50: 2.02E+5nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase [1-45,48-631](Human)
Keio University

Curated by ChEMBL
LigandPNGBDBM50221660(CHEMBL109045)
Affinity DataIC50: 6.66E+4nMAssay Description:Inhibitory activity against Acid sphingomyelinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50221660(CHEMBL109045)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed