BDBM50221533 4-((1R,2S)-2-(3-bromophenyl)cyclopropylamino)-6,7-dimethoxyquinoline-3-carbonitrile::CHEMBL248425

SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3cccc(Br)c3)c2cc1OC

InChI Key InChIKey=VEKGKQDLGQZPEO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221533   

TargetEpidermal growth factor receptor(Human)
Tanabe Research Laboratories Usa

Curated by ChEMBL
LigandPNGBDBM50221533(4-((1R,2S)-2-(3-bromophenyl)cyclopropylamino)-6,7-...)
Affinity DataKi:  52nMAssay Description:Inhibition of human recombinant EGFR by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed