BDBM50221451 (R)-3-amino-1-((R)-8-(cyclopropylmethyl)-2-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one::CHEMBL400752

SMILES N[C@@H](CC(=O)N1CCn2nc(nc2[C@H]1CC1CC1)C(F)(F)F)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=UBCLRDQHUNDJBO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221451   

TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221451((R)-3-amino-1-((R)-8-(cyclopropylmethyl)-2-(triflu...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221451((R)-3-amino-1-((R)-8-(cyclopropylmethyl)-2-(triflu...)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221451((R)-3-amino-1-((R)-8-(cyclopropylmethyl)-2-(triflu...)
Affinity DataIC50: 7nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221451((R)-3-amino-1-((R)-8-(cyclopropylmethyl)-2-(triflu...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed