BDBM50221435 4-((trans)-2-cyanocyclohexyloxy)-2-(trifluoromethyl)benzonitrile::CHEMBL399439

SMILES FC(F)(F)c1cc(O[C@H]2CCCC[C@@H]2C#N)ccc1C#N

InChI Key InChIKey=ARJGHPDXAXFKDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221435   

TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221435(4-((trans)-2-cyanocyclohexyloxy)-2-(trifluoromethy...)
Affinity DataIC50: 196nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221435(4-((trans)-2-cyanocyclohexyloxy)-2-(trifluoromethy...)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed