BDBM50221257 4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-(4-methylpentan-2-ylidene)semicarbazide::CHEMBL235506

SMILES CC(C)CC=NNC(=O)Nc1nnc(S)s1

InChI Key InChIKey=PINOROQDJJEYIM-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50221257   

TargetThymidylate synthase(Mouse)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50221257(4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-(...)
Affinity DataKi:  7.30E+3nMAssay Description:Time-independent inhibition of thymidylate synthase from parenteral L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50221257(4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-(...)
Affinity DataKi:  8.53E+3nMAssay Description:Inhibition of human cloned carbonic anhydrase1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50221257(4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-(...)
Affinity DataKi:  8.83E+3nMAssay Description:Inhibition of catalytic domain of human cloned carbonic anhydrase9 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50221257(4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-(...)
Affinity DataKi:  8.85E+3nMAssay Description:Inhibition of human cloned carbonic anhydrase2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50221257(4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-(...)
Affinity DataKi:  1.60E+4nMAssay Description:Compound was evaluated for the inhibition of dTMP synthetase with respect to dUMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed