BDBM50221069 (+)-haemanthamine::CHEMBL401114

SMILES CO[C@H]1C[C@H]2[C@]3(C=C1)c4cc5c(cc4CN2C[C@@H]3O)OCO5

InChI Key InChIKey=YGPRSGKVLATIHT-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50221069   

TargetAcetylcholinesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50221069((+)-haemanthamine | CHEMBL401114)
Affinity DataIC50: 4.52E+5nMAssay Description:Inhibition of AChE by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Defence

Curated by ChEMBL
LigandPNGBDBM50221069((+)-haemanthamine | CHEMBL401114)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate measured for 1 min by spectrophotometric based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50221069((+)-haemanthamine | CHEMBL401114)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured for 1 min by spectrophotometric based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed