BDBM50221001 CHEMBL76257

SMILES COc1ccc(cc1OC1CCCC1)C(=N\NC(C)=O)\c1ccccc1

InChI Key InChIKey=NKZLTJQXEQEIKS-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221001   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Lead Gene

Curated by ChEMBL

LigandBDBM50221001(CHEMBL76257)Copy SMILESCopy InChI

Affinity DataIC50: 3.70nMAssay Description:Inhibitory activity against purified rat liver phosphodiesterase 4More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/13/2018
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Lead Gene

Curated by ChEMBL

LigandBDBM50221001(CHEMBL76257)Copy SMILESCopy InChI

Affinity DataKi:  2nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/13/2018
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL