BDBM50221000 CHEMBL431962

SMILES CCC(=O)N\N=C(/c1ccccc1)c1ccc(OC)c(OC2CCCC2)c1

InChI Key InChIKey=HQMXWMFFIXBLOD-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221000   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Lead Gene

Curated by ChEMBL

LigandBDBM50221000(CHEMBL431962)Copy SMILESCopy InChI

Affinity DataIC50: 4.90nMAssay Description:Inhibitory activity against purified rat liver phosphodiesterase 4More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/13/2018
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Lead Gene

Curated by ChEMBL

LigandBDBM50221000(CHEMBL431962)Copy SMILESCopy InChI

Affinity DataKi: >5nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/13/2018
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL