BDBM50220993 CHEMBL78238

SMILES COc1ccc(cc1OC1CCCC1)C(=N\N=C(\N)S)\c1ccccc1

InChI Key InChIKey=WUXIKGOYVPMCLW-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220993   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Lead Gene

Curated by ChEMBL

LigandBDBM50220993(CHEMBL78238)Copy SMILESCopy InChI

Affinity DataIC50: 1.60nMAssay Description:Inhibitory activity against purified rat liver phosphodiesterase 4More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/13/2018
Entry Details Article
Copy Entry DOIPubMed
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Lead Gene

Curated by ChEMBL

LigandBDBM50220993(CHEMBL78238)Copy SMILESCopy InChI

Affinity DataKi:  2.30nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/13/2018
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL