BDBM50220927 (R)-1-(adamantan-1-ylamino)-3-(1H-indol-4-yloxy)-propan-2-ol::CHEMBL393522

SMILES O[C@H](CNC12CC3CC(CC(C3)C1)C2)COc1cccc2[nH]ccc12

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220927   

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50220927((R)-1-(adamantan-1-ylamino)-3-(1H-indol-4-yloxy)-p...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]DPAT from human 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50220927((R)-1-(adamantan-1-ylamino)-3-(1H-indol-4-yloxy)-p...)
Affinity DataKi:  30nMAssay Description:Antagonist activity at human 5HT1A expressed in mouse LM(tK-) cells assessed as inhibition of 5-HT-stimulated [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed