BDBM50220879 8-chloro-2-(3-(4-(4-fluorophenyl)piperidin-1-yl)propyl)quinazolin-4(3H)-one::CHEMBL250490

SMILES Fc1ccc(cc1)C1CCN(CCCc2nc3c(Cl)cccc3c(=O)[nH]2)CC1

InChI Key InChIKey=NDFQKILREVNCLZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220879   

TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220879(8-chloro-2-(3-(4-(4-fluorophenyl)piperidin-1-yl)pr...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50220879(8-chloro-2-(3-(4-(4-fluorophenyl)piperidin-1-yl)pr...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PARP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220879(8-chloro-2-(3-(4-(4-fluorophenyl)piperidin-1-yl)pr...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PARP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed