BDBM50220560 CHEMBL173962

SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1nccs1

InChI Key InChIKey=UEJDVRHNCIBADI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220560   

TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220560(CHEMBL173962)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibitory activity against human Nmt (HsNmt) using 0.5 uM peptide GNAASAR-R-NH2 and 0.5 uM myristoyl-CoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220560(CHEMBL173962)
Affinity DataIC50: 91nMAssay Description:In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220560(CHEMBL173962)
Affinity DataIC50: 6.30E+4nMAssay Description:In vitro inhibitory activity against Aspergillus fumigatus Nmt (AfNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed