BDBM50220385 4'-hydroxy-3-trifluoromethyl-biphenyl-4-carbonitrile::CHEMBL235378

SMILES Oc1ccc(cc1)-c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=JDHUDWCHCQEQBK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220385   

TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220385(4'-hydroxy-3-trifluoromethyl-biphenyl-4-carbonitri...)
Affinity DataIC50: 11.9nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220385(4'-hydroxy-3-trifluoromethyl-biphenyl-4-carbonitri...)
Affinity DataIC50: 61.2nMAssay Description:Displacement of [3H]DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220385(4'-hydroxy-3-trifluoromethyl-biphenyl-4-carbonitri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity at human PRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed