BDBM50220384 2',6'-dimethoxy-3-trifluoromethyl-biphenyl-4-carbonitrile::CHEMBL427678

SMILES COc1cccc(OC)c1-c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=SKHDYGGOADEMIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220384   

TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220384(2',6'-dimethoxy-3-trifluoromethyl-biphenyl-4-carbo...)
Affinity DataIC50: 14.7nMAssay Description:Displacement of [3H]DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220384(2',6'-dimethoxy-3-trifluoromethyl-biphenyl-4-carbo...)
Affinity DataIC50: 399nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed