BDBM50220317 CHEMBL236850::N-(diaminomethylene)-2-(2,4-diphenylthiophen-3-yl)acetamide

SMILES NC(=N)NC(=O)Cc1c(csc1-c1ccccc1)-c1ccccc1

InChI Key InChIKey=PPKBHBJOIMCNRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220317   

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50220317(N-(diaminomethylene)-2-(2,4-diphenylthiophen-3-yl)...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed