BDBM50220217 CHEMBL238138::[3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluoromethyl-benzyloxy)-biphenyl-4-yloxy]-acetic acid

SMILES OC(=O)COc1c(O)cc(cc1OCc1ccc(cc1)C(F)(F)F)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=QHFIVRUGDPOWOS-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50220217   

TargetTyrosine-protein phosphatase 1(Baker's yeast)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of yeast PTP1 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of TC-PTP after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of SHP-1 catalytic domain after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of TC-PTP after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed