BDBM50220077 2-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidine::CHEMBL393049

SMILES Clc1cc(Cl)cc(c1)-c1ncc2cccnc2n1

InChI Key InChIKey=UDWGFUUPZLVQFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220077   

TargetMetabotropic glutamate receptor 5(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220077(2-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidine | CH...)
Affinity DataIC50: 228nMAssay Description:Antagonistic activity at rat mGluR5 expressed in CHO cells assessed as inhibition of quisqualate stimulated calcium mobilization by FLIPR technologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed