BDBM50220041 CHEMBL229999::{[20-({dimethyl[(4-nitrophenyl)methyl]azaniumyl}methyl)-3,13-diazapentacyclo[11.7.0.0^{3,11}.0^{4,9}.0^{14,19}]icosa-1(20),4,6,8,10,14(19),15,17-octaen-10-yl]methyl}dimethyl[(4-nitrophenyl)methyl]azanium dibromide

SMILES C[N+](C)(Cc1c2Cn3c(Cn2c2ccccc12)c(C[N+](C)(C)Cc1ccc(cc1)[N+]([O-])=O)c1ccccc31)Cc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=DVZVHBUJNRUJGK-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50220041   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220041({[20-({dimethyl[(4-nitrophenyl)methyl]azaniumyl}me...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human alpha-7 nAChR in tsA201 cells coexpressed with Ric3 by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220041({[20-({dimethyl[(4-nitrophenyl)methyl]azaniumyl}me...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220041({[20-({dimethyl[(4-nitrophenyl)methyl]azaniumyl}me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human glycine alpha-1 receptor in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220041({[20-({dimethyl[(4-nitrophenyl)methyl]azaniumyl}me...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]methyllycaconitine from human alpha-7 in tsA201 cells coexpressed with 5HT3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220041({[20-({dimethyl[(4-nitrophenyl)methyl]azaniumyl}me...)
Affinity DataKi:  3.90E+3nMAssay Description:Displacement of [3H]methyllycaconitine from alpha7 nAChR in tsA201 cells co-expressed with Ric3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220041({[20-({dimethyl[(4-nitrophenyl)methyl]azaniumyl}me...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]GR65630 from human 5HT3A receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed