BDBM50219824 CHEMBL444824

SMILES COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2ccc(nc12)C#N

InChI Key InChIKey=MURWOQMZCQAOFK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219824   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219824(CHEMBL444824)
Affinity DataIC50: 43nMAssay Description:Inhibition of rolipram binding to PDE4 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50219824(CHEMBL444824)
Affinity DataIC50: 700nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50219824(CHEMBL444824)
Affinity DataIC50: 700nMAssay Description:Inhibition of PDE4 in Homo sapiens (human) U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article