BDBM50219500 2-Hydroxy-5-phenylbenzoic acid::4-Hydroxy-biphenyl-3-carboxylic acid::4-hydroxybiphenyl-3-carboxylic acid::CHEMBL121772

SMILES OC(=O)c1cc(ccc1O)-c1ccccc1

InChI Key InChIKey=LGERKUYJCZOBTB-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50219500   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50219500(2-Hydroxy-5-phenylbenzoic acid | 4-hydroxybiphenyl...)
Affinity DataIC50: 1.28E+6nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Research & Development, Abbvie

Curated by ChEMBL
LigandPNGBDBM50219500(2-Hydroxy-5-phenylbenzoic acid | 4-hydroxybiphenyl...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human recombinant MCL-1 (174 to 236) expressed in Escherichia coli BL21(DE3) using 6FAM-GELEVEFATQLRRFGDKLN as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Human)
University of Texas At San Antonio

Curated by ChEMBL
LigandPNGBDBM50219500(2-Hydroxy-5-phenylbenzoic acid | 4-hydroxybiphenyl...)
Affinity DataIC50: 4.29E+3nMAssay Description:Inhibition of human ACMSD using ACMS substrate by spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Tennessee

Curated by ChEMBL
LigandPNGBDBM50219500(2-Hydroxy-5-phenylbenzoic acid | 4-hydroxybiphenyl...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAlbumin(Human)
Molecular Discovery

Curated by ChEMBL
LigandPNGBDBM50219500(2-Hydroxy-5-phenylbenzoic acid | 4-hydroxybiphenyl...)
Affinity DataKi:  1.00E+5nMAssay Description:Binding affinity towards human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed