BDBM50219490 3-Bromo-5-phenylsalicylc acid::5-bromo-4-hydroxybiphenyl-3-carboxylic acid::CHEMBL387536

SMILES OC(=O)c1cc(cc(Br)c1O)-c1ccccc1

InChI Key InChIKey=XVZSXNULHSIRCQ-UHFFFAOYSA-N

Data  7 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50219490   

TargetAldo-keto reductase family 1 member C1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant 20-alpha HSD expressed in BAEC assessed as inhibition of progesterone metabolism treated 2 hrs before progesterone ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataIC50: 3.51E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataIC50: 460nMAssay Description:Inhibition of human AKR1C1-mediated progesterone metabolism expressed in bovine aortic endothelial cells assessed as formation of 20alpha-hydroxyprog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant 20-alpha HSD expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataKi:  4.10nMAssay Description:Inhibition of human wild type AKR1C1 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataKi:  4.10nMAssay Description:Inhibition of human recombinant AKR1C1 assessed as 1-acenaphthenol oxidation at 400 uM by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataKi:  87nMAssay Description:Inhibition of human recombinant type 3 3-alpha-HSD expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataKi:  87nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of human recombinant type 2 3-alpha-HSD expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataKi:  1.82E+4nMAssay Description:Inhibition of human recombinant type 1 3-alpha-HSD expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed