BDBM50219447 2-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl)-4,6-dimethylbenzonitrile::CHEMBL392501

SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc(C)cc(C)c1C#N)C(F)(F)F

InChI Key InChIKey=QEMGULFBAZGYKI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219447   

TargetMineralocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219447(2-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)
Affinity DataIC50: 250nMAssay Description:Displacement of TAMRA labeled mifepristone at human mineralocorticoid receptor in insect cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219447(2-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human progesterone receptor in insect cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219447(2-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)
Affinity DataIC50: 8nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed