BDBM50219446 3-fluoro-4-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl)benzonitrile::CHEMBL400609

SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1ccc(cc1F)C#N)C(F)(F)F

InChI Key InChIKey=ARAFJNZXJVLHDR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219446   

TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219446(3-fluoro-4-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy...)
Affinity DataIC50: 280nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human progesterone receptor in insect cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219446(3-fluoro-4-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy...)
Affinity DataIC50: 22nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219446(3-fluoro-4-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy...)
Affinity DataIC50: 500nMAssay Description:Displacement of TAMRA labeled mifepristone at human mineralocorticoid receptor in insect cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed