BDBM50219270 3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quinoline-5-carbonyl)-amino]-1-oxo-1,2-dihydro-pyridinium::3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quinoline-5-carbonyl)-amino]-pyridin-1-ol anion::8-methoxy-2-trifluoromethyl-quinoline-5-carboxylic acid (3,5-dichloro-1-oxy-pyridin-4-yl)-amide::CHEMBL250546

SMILES COc1ccc(C(=O)Nc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(nc12)C(F)(F)F

InChI Key InChIKey=RUOGJYKOQBFJIG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50219270   

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219270(3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE11More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219270(3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219270(3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quino...)
Affinity DataIC50: 60nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219270(3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quino...)
Affinity DataIC50: 150nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50219270(3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quino...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50219270(3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quino...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50219270(3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quino...)
Affinity DataIC50: 60nMAssay Description:Inhibition of PDE4 in Homo sapiens (human) U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article