BDBM50219116 CHEMBL396024::N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-hydroxybutyl)-9H-fluorene-2-carboxamide

SMILES OC(CCNC(=O)c1ccc-2c(Cc3ccccc-23)c1)CN1CCN(CC1)c1cccc(Cl)c1Cl

InChI Key InChIKey=RJAHNHBPWHWZAB-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50219116   

TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219116(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-hydr...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219116(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-hydr...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219116(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-hydr...)
Affinity DataKi:  319nMAssay Description:Displacement of [125I]IABN from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219116(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-hydr...)
Affinity DataKi:  545nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219116(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-hydr...)
Affinity DataKi:  1.81E+3nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219116(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-hydr...)
Affinity DataKi:  2.83E+3nMAssay Description:Binding affinity to human 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed