BDBM50219111 CHEMBL390253::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-2-hydroxybutyl)-4-(pyridin-2-yl)benzamide

SMILES OC(CCN1CCN(CC1)c1cccc(Cl)c1Cl)CNC(=O)c1ccc(cc1)-c1ccccn1

InChI Key InChIKey=ZQBFPGSJRSEUAX-UHFFFAOYSA-N

Data  5 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50219111   

TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219111(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-2-hydr...)
Affinity DataIC50: 88.3nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219111(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-2-hydr...)
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219111(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-2-hydr...)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219111(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-2-hydr...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219111(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-2-hydr...)
Affinity DataKi:  15.1nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219111(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-2-hydr...)
Affinity DataKi:  15.4nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219111(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-2-hydr...)
Affinity DataKi:  25.2nMAssay Description:Binding affinity to human 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219111(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-2-hydr...)
Affinity DataKi:  28.4nMAssay Description:Displacement of [125I]IABN from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed