BDBM50219047 CHEMBL245231::N-(3-(1-(4-(3,4-difluorophenoxy)benzyl)piperidin-4-yl)phenyl)isobutyramide::N-(3-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide

SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1

InChI Key InChIKey=MJDBJIACJNGVIM-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50219047   

TargetMelanin-concentrating hormone receptor 1(Rat)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219047(N-(3-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidi...)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at rat MCH1 receptor expressed in HEK293 cells by FLIPR calcium mobility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219047(N-(3-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidi...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of rat MCH1R receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219047(N-(3-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidi...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]T-226296 from rat recombinant MCH1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219047(N-(3-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidi...)
Affinity DataKi:  200nMAssay Description:Displacement of [125I]HEAT from human recombinant adrenergic alpha-1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219047(N-(3-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidi...)
Affinity DataKi:  470nMAssay Description:Displacement of [3H]spiperone from human recombinant dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed