BDBM50218964 CHEMBL44223

SMILES CC1(C)OC(=C(C1=O)c1cc(F)cc(F)c1)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=RKPRFFPVPAKVRJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50218964   

TargetProstaglandin G/H synthase 1(Mouse)
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50218964(CHEMBL44223)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibitory concentration against prostaglandin G/H synthase 1 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50218964(CHEMBL44223)
Affinity DataIC50: 52.9nMAssay Description:Inhibitory concentration against prostaglandin G/H synthase 2 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50218964(CHEMBL44223)
Affinity DataIC50: 79.3nMAssay Description:Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50218964(CHEMBL44223)
Affinity DataIC50: 5.28E+4nMAssay Description:Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50218964(CHEMBL44223)
Affinity DataIC50: 132nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50218964(CHEMBL44223)
Affinity DataIC50: 5.28E+4nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50218964(CHEMBL44223)
Affinity DataIC50: 132nMAssay Description:Inhibition of mouse COX-2 in LPS-induced mouse peritoneal macrophage assessed as reduction in PGE2 release incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed